Hi my sister is having trouble with her computer going slow there is a few things that look suspious on the log file but I dare not touch it without knowing for sure, I'll leave it to the experts so here's the hijack this log file and thank you for your time

Logfile of HijackThis v1.99.1
Scan saved at 8:42:15 PM, on 13/01/2006
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)

Running processes:
C:\WINNT\System32\smss.exe
C:\WINNT\system32\winlogon.exe
C:\WINNT\system32\services.exe
C:\WINNT\system32\lsass.exe
C:\WINNT\system32\svchost.exe
C:\WINNT\System32\svchost.exe
C:\WINNT\Explorer.EXE
C:\WINNT\system32\spoolsv.exe
C:\WINNT\System32\svchost.exe
C:\WINNT\system32\wscntfy.exe
C:\Program Files\Adaptec\Easy CD Creator 5\DirectCD\DirectCD.exe
C:\Program Files\QuickTime\qttask.exe
C:\Program Files\Common Files\Real\Update_OB\realsched.exe
C:\Program Files\Microsoft Hardware\Keyboard\type32.exe
C:\PROGRA~1\MYWEBS~1\bar\2.bin\mwsoemon.exe
C:\Program Files\Java\jre1.5.0_03\bin\jusched.exe
C:\WINNT\system32\ctfmon.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\MSN Messenger\MsnMsgr.Exe
C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
C:\Documents and Settings\Administrator\My Documents\LimeWire\LimeWire.exe
C:\PROGRA~1\GADWIN~1\PRINTS~1\PrintScreen.exe
C:\Program Files\Microsoft AntiSpyware\gcasDtServ.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\hijackthis\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = http://g.ninemsn.com.au/0SEENAU/SAOS01
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.bigpond.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = http://www.altavista.yellowpages.com.au/
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Window Title = BigPond Dial-Up Residential Internet Explorer
O2 - BHO: Yahoo! Toolbar Helper - {02478D38-C3F9-4EFB-9B51-7695ECA05670} - C:\Program Files\Yahoo!\Companion\Installs\cpn\yt.dll
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 6.0\Reader\ActiveX\AcroIEHelper.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\Program Files\Spybot - Search & Destroy\SDHelper.dll
O2 - BHO: ST - {9394EDE7-C8B5-483E-8773-474BF36AF6E4} - C:\Program Files\MSN Apps\ST\01.03.0000.1005\en-xu\stmain.dll
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - c:\program files\google\googletoolbar2.dll
O2 - BHO: MSNToolBandBHO - {BDBD1DAD-C946-4A17-ADC1-64B5B4FF55D0} - C:\Program Files\MSN Apps\MSN Toolbar\01.02.4000.1001\en-au\msntb.dll
O3 - Toolbar: ninemsn - {BDAD1DAD-C946-4A17-ADC1-64B5B4FF55D0} - C:\Program Files\MSN Apps\MSN Toolbar\01.02.4000.1001\en-au\msntb.dll
O3 - Toolbar: &Google - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - c:\program files\google\googletoolbar2.dll
O3 - Toolbar: Zango Toolbar - {EA0D26BD-9029-431A-86E0-83152D67828A} - C:\Program Files\Zango Programs\Zango Toolbar\ZangoTB.dll (file missing)
O3 - Toolbar: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\Program Files\Yahoo!\Companion\Installs\cpn\yt.dll
O4 - HKLM\..\Run: [Synchronization Manager] %SystemRoot%\system32\mobsync.exe /logon
O4 - HKLM\..\Run: [AdaptecDirectCD] C:\Program Files\Adaptec\Easy CD Creator 5\DirectCD\DirectCD.exe
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe" -osboot
O4 - HKLM\..\Run: [IntelliType] "C:\Program Files\Microsoft Hardware\Keyboard\type32.exe"
O4 - HKLM\..\Run: [gcasServ] "C:\Program Files\Microsoft AntiSpyware\gcasServ.exe"
O4 - HKLM\..\Run: [MyWebSearch Email Plugin] C:\PROGRA~1\MYWEBS~1\bar\2.bin\mwsoemon.exe
O4 - HKLM\..\Run: [SunJavaUpdateSched] C:\Program Files\Java\jre1.5.0_03\bin\jusched.exe
O4 - HKLM\..\Run: [zango] c:\program files\zango\zango.exe
O4 - HKCU\..\Run: [CTFMON.EXE] C:\WINNT\system32\ctfmon.exe
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - HKCU\..\Run: [MsnMsgr] "C:\Program Files\MSN Messenger\MsnMsgr.Exe" /background
O4 - HKCU\..\Run: [MyWebSearch Email Plugin] C:\PROGRA~1\MYWEBS~1\bar\2.bin\mwsoemon.exe
O4 - HKCU\..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
O4 - Startup: LimeWire On Startup.lnk = C:\Documents and Settings\Administrator\My Documents\LimeWire\LimeWire.exe
O4 - Startup: PrintScreen.lnk = C:\Program Files\Gadwin Systems\PrintScreen\UNWISE.EXE
O4 - Global Startup: Adobe Gamma Loader.lnk = C:\Program Files\Common Files\Adobe\Calibration\Adobe Gamma Loader.exe
O8 - Extra context menu item: &Google Search - res://c:\program files\google\GoogleToolbar2.dll/cmsearch.html
O8 - Extra context menu item: &Search - http://bar.mywebsearch.com/menusearch.html?p=ZNxmk311YYAU
O8 - Extra context menu item: &Translate English Word - res://c:\program files\google\GoogleToolbar2.dll/cmwordtrans.html
O8 - Extra context menu item: Backward Links - res://c:\program files\google\GoogleToolbar2.dll/cmbacklinks.html
O8 - Extra context menu item: Cached Snapshot of Page - res://c:\program files\google\GoogleToolbar2.dll/cmcache.html
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\OFFICE11\EXCEL.EXE/3000
O8 - Extra context menu item: Similar Pages - res://c:\program files\google\GoogleToolbar2.dll/cmsimilar.html
O8 - Extra context menu item: Translate Page into English - res://c:\program files\google\GoogleToolbar2.dll/cmtrans.html
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O14 - IERESET.INF: START_PAGE_URL=http://www.bigpond.com/
O16 - DPF: {8FCDF9D9-A28B-480F-8C3D-581F119A8AB8} - http://static.zangocash.com/cab/Zango/ie/bridge-c10.cab
O17 - HKLM\System\CCS\Services\Tcpip\..\{3B52FC44-3D22-4873-AE51-C8704ED908BE}: NameServer = 203.49.70.20 139.134.2.190
O18 - Protocol: msnim - {828030A1-22C1-4009-854F-8E305202313F} - "C:\PROGRA~1\MSNMES~1\msgrapp.dll" (file missing)
O23 - Service: Adobe LM Service - Unknown owner - C:\Program Files\Common Files\Adobe Systems Shared\Service\Adobelmsvc.exe

Have you sister join and we'll help her directly. I see some things and recommend uninstalling LimeWire. But I will not work on a system if the owner is unaware or doesn't agree.

K thought this might be the case. I will let her know cheers